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Components of the first line of defense include all the following except ________.


A) the tough cell sheet of the upper epidermis of the skin
B) nasal hairs
C) flushing action of tears and blinking
D) flushing action of urine
E) phagocytic white blood cells

F) D) and E)
G) A) and E)

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The leakage of excess fluid into tissues is called ________.


A) chemotaxis
B) edema
C) diapedesis
D) vasoactivity
E) pus

F) C) and D)
G) A) and D)

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Which protein can be produced by a virus-infected cell, in order to communicate with other cells the need to produce antiviral proteins?


A) Complement
B) Albumin
C) Interferon
D) Histamine

E) A) and D)
F) B) and C)

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B lymphocytes and T lymphocytes mature in the thymus gland.

A) True
B) False

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The patient asks the nurse to explain to him why he keeps getting sick from the same bacteria. Which of the following statements is the most appropriate response?


A) Your lungs produce these organisms because your cilia are permanently damaged.
B) Your mucus traps and harbors the microorganisms and when they can't be cleared, they begin to breach your second and third lines of defense.
C) Your disease stunts your immunity, so you are unable to fight those bacteria.
D) You don't have second and third line defenses because of your cystic fibrosis.

E) A) and B)
F) All of the above

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This body region is protected by fatty acids, acidic pH, lactic acid, and a tough cell barrier with its own normal biota.


A) Skin
B) Respiratory tract
C) Digestive tract
D) Urinary tract
E) Eyes

F) A) and C)
G) A) and B)

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Which of the following is incorrect about complement?


A) Is composed of at least 20 blood proteins
B) Only appears in the blood during a response to a pathogen
C) Acts in a cascade reaction
D) Involves a classical pathway
E) Involves an alternate pathway

F) B) and D)
G) A) and E)

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All of the following pertain to platelets except they ________.


A) contain hemoglobin to transport oxygen and carbon dioxide
B) function primarily in hemostasis
C) originate from giant multinucleate cells called megakaryocytes
D) function in blood clotting and inflammation
E) are not whole cells but are pieces of cells

F) C) and E)
G) None of the above

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Keratin is an important aspect of nonspecific defense because it ________.


A) is toxic to pathogens
B) creates a physical barrier against pathogens
C) destroys pathogens
D) physically restricts pathogens to a specific region
E) None of the choices are correct.

F) C) and D)
G) B) and D)

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Which of the following is not a mechanism employed by the human microbiota to contribute to the first line of defense?


A) It can phagocytose pathogens
B) It can lower the pH making the environment too acidic for pathogens to survive
C) It can out-compete pathogens for limited nutrients
D) It can train the immune cells to recognize antigenic markers
E) It can block potential binding sites on epithelial cells restricting adhesion, which is a necessary step for infection

F) A) and E)
G) None of the above

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The most numerous WBCs that have multilobed nuclei and are very phagocytic are ________.


A) basophils
B) eosinophils
C) neutrophils
D) monocytes
E) lymphocytes

F) B) and E)
G) None of the above

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Each of the following are benefits of fever except it ________.


A) reduces the ability of temperature-sensitive organisms to multiply
B) increases the availability of iron
C) increases phagocytosis
D) increases metabolism
E) stimulates hematopoiesis

F) B) and C)
G) B) and E)

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During what process are hypochlorite and hydrogen peroxide produced to destroy bacteria and inhibit viral replication?


A) Inflammation
B) Phagocytosis
C) Interferon production
D) Complement production
E) Bradykinin

F) A) and B)
G) A) and C)

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Which of the following is incorrect about inflammation?


A) It can last hours to years.
B) Pyrogens cause vasodilation and increased capillary permeability.
C) Serotonin causes smooth muscle contraction.
D) Fever could be beneficial to inhibiting the pathogen.
E) Basophils and mast cells release histamine.

F) A) and C)
G) All of the above

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The term ________ is given to any foreign substance that stimulates a specific immune system response.


A) antibody
B) allergen
C) antigen
D) foreign body
E) None of the choices are correct.

F) None of the above
G) A) and B)

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The granules of basophils contain ________.


A) antibodies
B) antigens
C) digestive enzymes
D) histamine
E) lysozyme

F) A) and E)
G) C) and D)

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Plasma ________.


A) is the liquid portion of blood in which blood cells are suspended
B) is mostly water
C) contains albumin and globulins
D) contains fibrinogen
E) All of the choices are correct.

F) A) and E)
G) B) and D)

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The lymphoid tissues of the intestinal tract are collectively referred to as ________.


A) lymph nodes
B) thymus
C) spleen
D) GALT
E) tonsils

F) A) and B)
G) B) and E)

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Which of the following is incorrect about circulating blood cells?


A) After birth, produced in red bone marrow sites
B) Develop from undifferentiated stem cells
C) Include Kupffer cells
D) Include leukocytes that are either granulocytes or agranulocytes
E) Include erythrocytes that, when mature, lose their nuclei

F) B) and D)
G) A) and B)

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The second line of defense is a series of systems that involves both cells and chemicals working together.

A) True
B) False

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