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Syphilis can be diagnosed by the


A) Weil-Felix reaction.
B) rapid plasma reagin test.
C) Widal test.
D) latex agglutination test.
E) antistreptolysin O test.

F) A) and C)
G) All of the above

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Soluble antigens are detected in this type of test.


A) cross reactions
B) agglutination
C) precipitation
D) specificity
E) sensitivity

F) None of the above
G) A) and B)

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The property of a test to detect even small amounts of antibodies or antigens that are test targets is


A) cross reaction.
B) agglutination.
C) precipitation.
D) specificity.
E) sensitivity.

F) B) and D)
G) C) and E)

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Which test uses radioactive isotopes to label antibodies or antigens in order to detect minute amounts of corresponding antigen or antibody?


A) Ouchterlony double diffusion
B) Western blot
C) immunelectrophoresis
D) radioimmunoassay (RIA)
E) Quellung

F) All of the above
G) A) and D)

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Serological testing relies upon


A) the specificity of the Fc region of antibodies.
B) the specificity of the variable regions of antibodies.
C) a patient who is not immunocompromised.
D) very high viral or bacterial load in the patient.
E) None of the choices is correct.

F) A) and B)
G) A) and C)

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B

The Weil-Felix test is used for diagnosing salmonellosis.

A) True
B) False

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Animals are required for the cultivation of


A) Treponema pallidum.
B) Pseudomonas.
C) Streptococcus.
D) Salmonella.
E) Clostridium.

F) None of the above
G) D) and E)

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A

Which sample is not typically collected by sterile needle aspiration?


A) blood
B) urine
C) cerebrospinal fluid
D) tissue fluids
E) All of the choices are collected by sterile needle aspiration.

F) A) and D)
G) C) and D)

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Precipitation tests involve all of the following except


A) they rely on formation of visible clumps for detection.
B) they include the VDRL test for syphilis.
C) they are often performed in agar gels.
D) they can be done in a test tube by carefully adding antiserum over antigen solution.
E) a cloudy or opaque zone developing where antigen and antibody react.

F) A) and B)
G) A) and E)

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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. Halley is a 62-year-old female, previously healthy with no significant medical history, and no known allergies. She is admitted to your medical-surgical floor for an infectious disease work-up. Halley has been experiencing generalized pain and nausea for the past 3 weeks, and recently developed a fever. The doctors at the urgent care center, and then the emergency department, were perplexed by her presentation. You have been ordered to perform several tests: complete blood count (CBC) , C-reactive protein (CRP) , eosinophil sedimentation rate (ESR) , blood culture, urine culture, and a lumbar puncture with cerebral spinal fluid (CSF) culture and cell count. You are also collecting a sputum culture, as well as swabbing her nose with a culturette, and performing a nasal wash. -Halley's nasal wash results came back,and were reported as "insufficient cells available for testing." What does this mean?


A) Halley is free of infection since insufficient cells could be isolated.
B) A smaller sample must be sent,since the counts clouded the results.
C) This is a very specific and sensitive finding that points to a viral infection.
D) The sample was inadequate,and the nasal wash procedure must be repeated.

E) A) and D)
F) All of the above

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Which test is especially good for bacteria that are not readily cultivated in the lab?


A) Gram stain
B) direct antigen testing
C) dichotomous key
D) direct fluorescence antibody (DFA) testing
E) phage test

F) A) and B)
G) All of the above

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It is necessary to do lab tests to diagnose all diseases.

A) True
B) False

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Antibody testing requires


A) a known antigen.
B) a known antibody.
C) both a known antigen and a known antibody.
D) either a known antigen or a known antibody.

E) A) and B)
F) A) and C)

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The Western blot test is confirmatory for HIV because


A) it is more sensitive than the ELISA.
B) it has fewer false positives than the ELISA.
C) it tests for more HIV antibodies than ELISA.
D) it is easier to interpret than ELISA.
E) All of the choices are correct.

F) A) and B)
G) B) and D)

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A positive serological test for tuberculosis indicates that


A) the patient has active tuberculosis.
B) the patient is an asymptomatic carrier of tuberculosis.
C) the patient has been exposed to tuberculosis.
D) All of the choices are correct.

E) None of the above
F) B) and C)

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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. Jared is a 34-year-old male who has reported several weeks of general malaise, and a low-grade fever. You are a nurse working for the public health department, and you are corresponding with Jared concerning the results of his laboratory testing. -Jared informs you that he previously had a negative HIV PCR test performed about a month ago.What is your interpretation of this information?


A) PCRs are rarely accurate.
B) He may be lying,since the ELISA came back positive.
C) It is possible the ELISA was a false-positive,and the Western blot must be performed to confirm.
D) The HIV PCR is outdated,and does not pick up modern strains of the virus.

E) B) and D)
F) B) and C)

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C

The tuberculin test is an example of an in vitro serological test.

A) True
B) False

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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. Tyler is a 16-year-old male who has come into your clinic with a low-grade fever, and large and painful red sores around his lips. He has a PCR test pending that was swabbed from the sores, as well as a blood culture with Gram stain, and nasal wash for examination by microscope. -What kind of evidence are the sores around Tyler's mouth classified as?


A) signs and symptoms
B) ELISA
C) genetic evidence
D) microscopic evidence

E) A) and C)
F) A) and B)

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Biochemical tests include all of the following except


A) presence of catalase.
B) presence of oxidase.
C) colony morphology.
D) sugar fermentation.
E) gas production.

F) C) and D)
G) A) and E)

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Serological testing always involves reactions between specific antibody and antigen.

A) True
B) False

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