Question 1

Point mutations

Accepted Answer

A)   are due to a change in one DNA nucleotide.
B)   may change a specific codon.
C)   can cause a genetic disease such as sickle cell disease that is due to a base change that codes for valine rather than glutamate.
D)   All of the choices are correct.E) All of the above
F) A) and D)

Question 2

Which of the following problems can arise during posttransriptional control?

Accepted Answer

A)   Differential splicing of exons that can lead to an altered gene expression.
B)   Not excising all of introns from the pre-mRNA strand, leaving fragments to be joined with the exons.
C)   Excising an exon from the pre-mRNA strand.
D)   All of these are errors that can occur during posttranscriptional control of gene expression.E) A) and B)
F) None of the above

Question 3

Androgen insensitivity is characterized by

Accepted Answer

A)   a lack of male hormones, such as testosterone.
B)   external female genitalia.
C)   a female karyotype.
D)   the internal sex organs of a female and may bear children.E) None of the above
F) A) and B)

Question 4

Frameshift mutations

Accepted Answer

A)   most often happen when one or more nucleotides are inserted or deleted from the DNA.
B)   can result in a completely new codon sequence that results in the production of non-functional proteins.
C)   applies to the reading frame (sequence of codons)  being changed.
D)   All of the choices are correct.E) None of the above
F) B) and C)

Question 5

The most critical level of eukaryotic genetic control is ________ control.

Accepted Answer

A)   feedback
B)   translational
C)   transcriptional
D)   posttranscriptional
E)   posttranslationalF) B) and D)
G) C) and E)

Question 6

Germ-line mutations

Accepted Answer

A)   occur in sex cells.
B)   can be passed to subsequent generations.
C)   may range from having no effect to completely inactivating protein activity.
D)   All of the answer choices are true about germ line mutations.
E)   Only two of the answer choices are true.F) C) and E)
G) A) and E)

Question 7

Which of the following situations would be considered an example of positive regulation of gene expression in a prokaryote?

Accepted Answer

A)   The CAP protein regulating the lac operon to be active when glucose is absent and lactose is present.
B)   The CAP protein regulating the lac operon to be active when lactose is absent and glucose is present.
C)   The repressor protein regulating the lac operon to be active when glucose is absent and lactose is present.
D)   The repressor protein regulating the lac operon to be active when lactose is absent and glucose is present.E) B) and C)
F) C) and D)

Question 8

Explain how the trp operon is regulated in a prokaryotic cell when tryptophan is present.

Accepted Answer

Answers may vary but should include the ...

Question 9

The mRNA strand includes both introns and exons.

Accepted Answer

A) True 
 B)False

Question 10

Match the level of gene expression control with the location of that control.

Accepted Answer

The answer of Match the level of gene expression control...

Question 11

The level of genetic control that involves the processing of early RNA transcripts to mRNA and the rate at which mRNA leaves the nucleus is

Accepted Answer

A)   feedback control.
B)   translational control.
C)   transcriptional control.
D)   posttranscriptional control.
E)   posttranslational control.F) A) and B)
G) A) and C)

Question 12

In the lac operon, if lactose is present, which of the following occurs?

Accepted Answer

A)   Lactose binds to the repressor, changing its shape so that it can bind to the operator and the structural genes are not expressed.
B)   Lactose bind to RNA polymerase, which then binds to the promoter and transcribes the needed genes.
C)   Lactose binds to the repressor, changing its shape so that it does not bind to the operator. RNA polymerase then transcribes the needed genes.
D)   Lactose binds to the operon, which attracts RNA polymerase, then transcription of the needed genes occurs.E) B) and C)
F) None of the above

Question 13

The term "operon" comes from the Latin root word for

Accepted Answer

A)   gene.
B)   structure.
C)   controller.
D)   work.
E)   copy-producing.F) B) and C)
G) All of the above

Question 14

Which component in an operon is incorrectly matched with its function?

Accepted Answer

A)   promoter-where RNA polymerase first binds to DNA
B)   regulator gene-binds to the repressor protein
C)   structural gene-makes mRNA by transcription
D)   operator-if not bound to repressor, allows RNA polymerase to bind to DNAE) All of the above
F) B) and C)

Question 15

A change in a regulatory gene

Accepted Answer

A)   must be dominant to be effective.
B)   is what happens in the production of sickle cell hemoglobin.
C)   is always beneficial to the organism in which it occurs.
D)   can increase or decrease the expression of a structural gene.E) B) and C)
F) A) and C)

Question 16

Which of the following structures is not part of an operon?

Accepted Answer

A)   regulator gene
B)   promoter
C)   operator
D)   structural gene
E)   all of these are part of an operonF) None of the above
G) B) and E)

Question 17

____________ occurs as ____________ builds up in the system if Enzyme A is nonfunctional because of an inherited mutation
)

Accepted Answer

A)   albinism; melanin
B)   xeroderma pigmentosum; tyrosine
C)   phenylketonuria; phenyalanine
D)   androgen insensitivity; tyrosineE) None of the above
F) All of the above

Question 18

Which level of primary control in eukaryotic gene activity involves changes in the polypeptide chain before it becomes functional?

Accepted Answer

A)   feedback control
B)   translational control
C)   transcriptional control
D)   posttranscriptional control
E)   posttranslational controlF) D) and E)
G) All of the above

Question 19

Once proteins are made and functional, they are no longer subject to cellular control.

Accepted Answer

A) True 
 B)False

Question 20

You are more likely to develop some forms of cancer if you

Accepted Answer

A)   are exposed to higher doses of radiation including X rays.
B)   are exposed to carcinogens.
C)   have a high incidence of cancer in your family history.
D)   All of the choices are correct.E) B) and D)
F) A) and B)

Exam 13: Regulation of Gene Expression

The term "operon" comes from the Latin root word for

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Which of the following problems can arise during posttransriptional control?

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Germ-line mutations

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Which of the following structures is not part of an operon?

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____________ occurs as ____________ builds up in the system if Enzyme A is nonfunctional because of an inherited mutation )

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Which of the following situations would be considered an example of positive regulation of gene expression in a prokaryote?

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Frameshift mutations

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Once proteins are made and functional, they are no longer subject to cellular control.

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Match the level of gene expression control with the location of that control.

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Point mutations

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The mRNA strand includes both introns and exons.

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Which level of primary control in eukaryotic gene activity involves changes in the polypeptide chain before it becomes functional?

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Explain how the trp operon is regulated in a prokaryotic cell when tryptophan is present.

Correct AnswerverifiedAnswers may vary but should include the ...View AnswerShow Answer

A change in a regulatory gene

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You are more likely to develop some forms of cancer if you

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Androgen insensitivity is characterized by

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The most critical level of eukaryotic genetic control is ________ control.

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Which component in an operon is incorrectly matched with its function?

Correct AnswerverifiedShow Answer

The level of genetic control that involves the processing of early RNA transcripts to mRNA and the rate at which mRNA leaves the nucleus is

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In the lac operon, if lactose is present, which of the following occurs?

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occurs as builds up in the system if Enzyme A is nonfunctional because of an inherited mutation )

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Answers may vary but should include the ...
View Answer

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